Ookami Kodomo no Ame to Yuki (2012)

Hana, a nineteen-year-old college student, falls in love with a man only for him to reveal his secret; he is a Wolf Man. Eventually the couple bear two children together; a son and daughter they name Ame and Yuki who both inherit the ability to transform into wolves from their father. When the man Hana fell in love with suddenly dies, she makes the decision to move to a rural town isolated from society to continue raising the children in protection.